Gorman D G, Cummings J L
Department of Neurology, UCLA School of Medicine.
J Neuropsychiatry Clin Neurosci. 1993 Winter;5(1):37-42. doi: 10.1176/jnp.5.1.37.
Antiphospholipid antibodies, including lupus anticoagulant and anticardiolipin antibodies, are increasingly recognized as a cause of neurological morbidity. They may occur with or without evidence of systemic lupus erythematosus and have been associated with stroke, migraine, and confusional states. Their role as etiologic or contributing factors in neurobehavioral and neuropsychiatric syndromes of obscure etiology has not been emphasized. The cases of 7 patients who were referred for evaluation of behavior abnormalities and had antiphospholipid antibodies are presented, and the potential relationships of the antiphospholipid antibody syndrome to behavioral alterations are discussed.
抗磷脂抗体，包括狼疮抗凝物和抗心磷脂抗体，越来越被认为是神经功能障碍的一个病因。它们可能在有或没有系统性红斑狼疮证据的情况下出现，并与中风、偏头痛和意识模糊状态有关。它们在病因不明的神经行为和神经精神综合征中作为病因或促成因素的作用尚未得到重视。本文介绍了7例因行为异常接受评估且患有抗磷脂抗体的患者病例，并讨论了抗磷脂抗体综合征与行为改变之间的潜在关系。
