• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Azathioprine-induced myelosuppression in thiopurine methyltransferase deficient heart transplant recipient.

作者信息

Schütz E, Gummert J, Mohr F, Oellerich M

出版信息

Lancet. 1993 Feb 13;341(8842):436. doi: 10.1016/0140-6736(93)93028-y.

DOI:10.1016/0140-6736(93)93028-y
PMID:8094196
Abstract
摘要

相似文献

1
Azathioprine-induced myelosuppression in thiopurine methyltransferase deficient heart transplant recipient.
Lancet. 1993 Feb 13;341(8842):436. doi: 10.1016/0140-6736(93)93028-y.
2
Azathioprine-induced myelosuppression in thiopurine methyltransferase deficient heart transplant recipient.硫嘌呤甲基转移酶缺乏的心脏移植受者中硫唑嘌呤诱导的骨髓抑制。
Lancet. 1993 May 1;341(8853):1151. doi: 10.1016/0140-6736(93)93168-z.
3
Severe azathioprine-induced myelotoxicity in a kidney transplant patient with thiopurine S-methyltransferase-deficient genotype (TPMT*3A/*3C).硫嘌呤甲基转移酶缺陷基因型(TPMT*3A/*3C)的肾移植患者发生严重的硫唑嘌呤诱导的骨髓毒性。
Transpl Int. 2005 May;18(5):623-5. doi: 10.1111/j.1432-2277.2005.00095.x.
4
Azathioprine-induced myelosuppression due to thiopurine methyltransferase deficiency in a patient with autoimmune hepatitis.一名自身免疫性肝炎患者因硫嘌呤甲基转移酶缺乏导致硫唑嘌呤引起的骨髓抑制。
J Hepatol. 1995 Sep;23(3):351-4. doi: 10.1016/0168-8278(95)80481-1.
5
Two cases of thiopurine methyltransferase (TPMT) deficiency--a lucky save and a near miss with azathioprine.两例硫嘌呤甲基转移酶(TPMT)缺乏症——使用硫唑嘌呤时一次幸运的挽救和一次险些酿成的大祸。
Br J Clin Pharmacol. 2006 Oct;62(4):473-6. doi: 10.1111/j.1365-2125.2005.02474.x.
6
[Homozygote deficiency of thiopurine methyltransferase. A contraindication to the use of azathioprine in kidney transplantation].[硫嘌呤甲基转移酶纯合子缺乏症。肾移植中使用硫唑嘌呤的禁忌证]
Presse Med. 1995 Sep 23;24(27):1257-9.
7
Azathioprine and diffuse alveolar haemorrhage: the pharmacogenetics of thiopurine methyltransferase.硫唑嘌呤与弥漫性肺泡出血:硫嘌呤甲基转移酶的药物遗传学
Eur Respir J. 2007 Nov;30(5):1014-7. doi: 10.1183/09031936.00026107.
8
Fatal myelotoxicity after azathioprine treatment.硫唑嘌呤治疗后发生的致命性骨髓毒性。
Nucleosides Nucleotides Nucleic Acids. 2008 Jun;27(6):661-5. doi: 10.1080/15257770802143905.
9
Thiopurine-methyl-transferase activity to assess azathioprine myelotoxicity in renal transplant recipients.通过硫嘌呤甲基转移酶活性评估肾移植受者中硫唑嘌呤的骨髓毒性。
Lancet. 1993 Jun 19;341(8860):1593-4. doi: 10.1016/0140-6736(93)90729-z.
10
Azathioprine and 6-mercaptopurine pharmacogenetics and metabolite monitoring in inflammatory bowel disease.炎症性肠病中硫唑嘌呤和6-巯基嘌呤的药物遗传学及代谢物监测
J Gastroenterol Hepatol. 2005 Aug;20(8):1149-57. doi: 10.1111/j.1440-1746.2005.03832.x.

引用本文的文献

1
and genotyping, TPMT enzyme activity and metabolite determination for thiopurines therapy: a reference laboratory experience.硫嘌呤类药物治疗的基因分型、TPMT酶活性及代谢物测定:参考实验室经验
Pharmacogenomics. 2024;25(16-18):679-688. doi: 10.1080/14622416.2025.2463866. Epub 2025 Feb 16.
2
Mechanisms of -Mediated Thiopurine Resistance in Acute Lymphoblastic Leukemia.-Mediated 硫嘌呤耐药在急性淋巴细胞白血病中的机制。
Mol Cancer Ther. 2019 Oct;18(10):1887-1895. doi: 10.1158/1535-7163.MCT-18-1112. Epub 2019 Jul 29.
3
Association Between Thiopurine S-Methyltransferase () Genetic Variants and Infection in Pediatric Heart Transplant Recipients Treated With Azathioprine: A Multi-Institutional Analysis.
硫嘌呤 S-甲基转移酶()基因变异与接受硫唑嘌呤治疗的小儿心脏移植受者感染之间的关联:一项多机构分析。
J Pediatr Pharmacol Ther. 2018 Mar-Apr;23(2):106-110. doi: 10.5863/1551-6776-23.2.106.
4
Role of autophagy in the pathogenesis of inflammatory bowel disease.自噬在炎症性肠病发病机制中的作用。
World J Gastroenterol. 2017 Mar 21;23(11):1944-1953. doi: 10.3748/wjg.v23.i11.1944.
5
Pharmacogenomics and personalized medicine: a review focused on their application in the Chinese population.药物基因组学与个性化医疗:一项聚焦于其在中国人群中应用的综述
Acta Pharmacol Sin. 2015 May;36(5):535-43. doi: 10.1038/aps.2015.10. Epub 2015 Apr 20.
6
Pharmacogenomics--how close/far are we to practising individualized medicine for children?药物基因组学——我们距离为儿童实施个性化医疗还有多远/近?
Br J Clin Pharmacol. 2015 Mar;79(3):419-28. doi: 10.1111/bcp.12338.
7
Polymorphisms of the thiopurine S-methyltransferase gene among the Libyan population.利比亚人群中硫嘌呤甲基转移酶基因的多态性
Libyan J Med. 2015 Mar 26;10(1):27053. doi: 10.3402/ljm.v10.27053. eCollection 2015.
8
Assessment of Thiopurine-based drugs according to Thiopurine S-methyltransferase genotype in patients with Acute Lymphoblastic Leukemia.根据硫嘌呤甲基转移酶基因型对急性淋巴细胞白血病患者使用硫嘌呤类药物的评估。
Iran J Ped Hematol Oncol. 2014;4(1):32-8. Epub 2014 Apr 20.
9
Implementation of TPMT testing.硫嘌呤甲基转移酶(TPMT)检测的实施
Br J Clin Pharmacol. 2014 Apr;77(4):704-14. doi: 10.1111/bcp.12226.
10
Cancer pharmacogenomics in children: research initiatives and progress to date.儿童癌症药物基因组学:研究计划和迄今为止的进展。
Paediatr Drugs. 2013 Apr;15(2):71-81. doi: 10.1007/s40272-013-0021-9.