Fracchia J, Sheppard C, Canale D, Ruest E, Cambria E, Merlis S
J Am Geriatr Soc. 1975 Nov;23(11):508-11. doi: 10.1111/j.1532-5415.1975.tb00897.x.
The dosage levels for a number of frequently prescribed psychotropic drugs, used singly or in combination, were determined in 902 long-term psychogeriatric hospital patients. The data failed to support the hypothesis that physicians prescribe lower dosages when combination therapy is used. Rather, the tendency was toward higher dosages under these circumstances.
对902名长期住院的老年精神科患者,测定了多种单独或联合使用的常用精神药物的剂量水平。数据未能支持医生在使用联合治疗时会开较低剂量药物这一假设。相反,在这些情况下,有使用更高剂量的趋势。