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磺苄西林和羧苄西林对铜绿假单胞菌作用的比较。

Comparison of suncillin and carbenicillin effect on Pseudomonas aeruginosa.

作者信息

Chaloupecký V, Výmola F

出版信息

J Hyg Epidemiol Microbiol Immunol. 1975;19(2):217-23.

PMID:809502
Abstract

The semisynthetic penicillin suncillin was compared in vitro with carbenicillin for its effectiveness against different P. aeruginosa strains and for stability in solution. Carbenicillin was about twice as effective against the strains employed, while suncillin maintained its activity in saline for a longer time. The induction of resistance to suncillin was accompanied by the simultaneous development of resistance to the other antibiotic.

摘要

对半合成青霉素磺苄西林与羧苄西林进行了体外比较,以研究它们对不同铜绿假单胞菌菌株的有效性以及在溶液中的稳定性。羧苄西林对所用菌株的有效性约为磺苄西林的两倍,而磺苄西林在盐溶液中的活性维持时间更长。对磺苄西林耐药性的诱导伴随着对另一种抗生素耐药性的同时产生。

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