Jedlicková Z, Sulová J
Zentralbl Bakteriol Orig A. 1975 Jan;230(1):104-11.
Effects of a new antimicrobial agent sisomicin on microorganisms isolated from pathologic material (Pseudomonas aeruginosa, Staphylococcus aureus, Serratia marcescens, Klebsiella pneumoniae, Salmonella spp., Streptococcus pyogenes-B, Citrobacter Freundii) were studied. The results obtained were compared with another two aminoglycoside antibiotics - gentamicin and tobramycin. All three antibiotics were found to be very effective in vitro; their effect was enhanced by addition of an antibiotic of the penicillin group (carbenicillin, suncillin) or an antibiotic of the tetracyklin series (oxytetracyklin, doxycyklin). All three preparations were tested on 26 Mycobacterium tuberculosis strains. Tobramycin inhibited growth of 22 strains and thus presented the highest level of efficiency among these deoxystreptamin preparations.
研究了一种新型抗菌剂西索米星对从病理材料中分离出的微生物（铜绿假单胞菌、金黄色葡萄球菌、粘质沙雷氏菌、肺炎克雷伯菌、沙门氏菌属、化脓性链球菌B群、弗氏柠檬酸杆菌）的作用。将所得结果与另外两种氨基糖苷类抗生素——庆大霉素和妥布霉素进行了比较。发现所有三种抗生素在体外都非常有效；通过添加青霉素类抗生素（羧苄青霉素、磺苄青霉素）或四环素类抗生素（土霉素、强力霉素）可增强它们的作用。对26株结核分枝杆菌菌株测试了所有三种制剂。妥布霉素抑制了22株菌株的生长，因此在这些脱氧链霉胺制剂中表现出最高的效率水平。
