Dadoukis J D, Papavramidis S T, Karkavelas G N, Aidonopoulos A P, Aletras H A
Department of Surgery, Aristotelian University of Thessaloniki, School of Medicine, AHEPA Hospital, Macedonia, Greece.
Eur J Surg. 1993 Jan;159(1):31-3.
To find out if pedicle grafts of peritoneum and transversalis muscle could be used to repair large defects in the wall of the duodenum.
Experimental study.
18 healthy mongrel dogs.
Defects were created in the second part of duodenum and repaired with pedicle grafts of peritoneum and transversalis muscle from the anterior wall of the right side of the abdomen.
Postoperative complications, appearances on upper gastrointestinal radiography two and four months after operation, and histological examination of necropsy specimens.
There were no postoperative deaths or complications. Radiographs of the duodenum showed no abnormalities and in particular no signs of obstruction. Animals were killed at intervals from one week to eight months after operation, and the only abnormality was 20-30% stenosis found in five dogs killed within two months of operation, which did not affect gastric emptying. Histological examination showed that by four months after operation the patch was completely covered by neomucosa that was similar to normal duodenal mucosa. By six months the site of the defect was well healed and the histological appearance was the same as at four months.
Pedicle grafts of peritoneum and transversalis muscle may be useful in the treatment of patients with large defects in the wall of the duodenum.
探究腹膜和腹横肌带蒂移植物是否可用于修复十二指肠壁的大缺损。
实验研究。
18只健康杂种犬。
在十二指肠第二部制造缺损，并用取自右侧腹前壁的腹膜和腹横肌带蒂移植物进行修复。
术后并发症、术后2个月和4个月时上消化道造影表现以及尸检标本的组织学检查。
无术后死亡或并发症。十二指肠造影未见异常，尤其无梗阻迹象。术后1周8个月期间分批处死动物，唯一异常是在术后2个月内处死的5只犬中发现有20%30%的狭窄，这并未影响胃排空。组织学检查显示，术后4个月时补片完全被类似于正常十二指肠黏膜的新黏膜覆盖。到6个月时，缺损部位愈合良好，组织学表现与4个月时相同。
腹膜和腹横肌带蒂移植物可能对治疗十二指肠壁大缺损患者有用。
