Juergens S M
Virginia Mason Outpatient Chemical Dependency Program, Virginia Mason Clinic.
Psychiatr Clin North Am. 1993 Mar;16(1):75-86.
Benzodiazepines are medications that are addicting--both in combination with other drugs and alone. The scope of the problem is thought to be wide, but it has not been well documented for unclear reasons. Pharmacologic dependence has been documented in virtually all long-term users. Adverse effects occur secondary to their use and these effects are often subtle, but significant. Various benzodiazepines present differences in reinforcement, withdrawal, and adverse effects. Diagnostic issues, withdrawal, and treatment issues are discussed.
苯二氮䓬类药物具有成瘾性——无论是与其他药物合用还是单独使用。人们认为这一问题的范围很广，但由于不明原因，相关记录并不完善。几乎所有长期使用者都有药物依赖性记录。使用这类药物会产生副作用，这些副作用往往很细微，但却很严重。不同的苯二氮䓬类药物在强化作用、戒断反应和副作用方面存在差异。本文将讨论诊断问题、戒断反应和治疗问题。
