Madsen J K, Hansen J F
Department of Cardiology, Hvidovre Hospital, Copenhagen, Denmark.
Eur Heart J. 1993 Mar;14(3):377-9. doi: 10.1093/eurheartj/14.3.377.
The 18 month mortality rate in 2180 patients excluded from the Danish Verapamil Infarction Trail II (DAVIT II) was 25.6%. In non-consenters (n = 368) this was 15.0% compared with 13.85 in 897 placebo-treated patients (hazard ratio 1.09 [P = 0.60] when adjusting for sex and age). The increased mortality rate in excluded patients is attributed to heart failure (45.8%) and other severe diseases (38.9%).
被排除在丹麦维拉帕米梗死试验II(DAVIT II)之外的2180名患者的18个月死亡率为25.6%。在未同意参与试验者(n = 368)中,这一比例为15.0%,而在897名接受安慰剂治疗的患者中为13.85%(在对性别和年龄进行校正后,风险比为1.09 [P = 0.60])。被排除患者死亡率的增加归因于心力衰竭(45.8%)和其他严重疾病(38.9%)。