Hull M A, Rawlings J, Murray F E, Field J, McIntyre A S, Mahida Y R, Hawkey C J, Allison S P
Department of Medicine, University Hospital, Queen's Medical Centre, Nottingham, UK.
Lancet. 1993 Apr 3;341(8849):869-72. doi: 10.1016/0140-6736(93)93072-9.
Percutaneous endoscopic gastrostomy (PEG) is the preferred method for administration of long-term enteral tube feeding. However, most published studies describe only short-term follow-up in any detail. We report the long-term outcome and complication rate after PEG insertion in 49 patients (mean [SE] age 64 [2] years) whose mean length of PEG feeding was 175 days (range 30-560). Data were collected prospectively. PEG insertion was technically successful in all cases, with a procedure-related mortality of 2%. Early (< 30 days) mortality and morbidity were 8% and 22%, respectively. Of 45 patients surviving for more than 30 days, 76% were able to return home and 6 patients were eventually able to revert to oral feeding. There were 27 late complications: 2 site infections, 17 mechanical problems, and 8 episodes of gastrointestinal dysfunction. 51% of patients had no problems at all and 22% had 2 or more complications. 47% of complications required a hospital visit for resolution. Long-term enteral feeding by PEG was safe, effective, and had a low complication rate. Our patients were managed by a specialist nutrition team, a policy that may reduce the complication rate and hospital visits for patients being fed at home, and allow early discharge of dysphagic patients, thereby reducing costs.
经皮内镜下胃造口术(PEG)是长期肠内管饲的首选方法。然而,大多数已发表的研究仅详细描述了短期随访情况。我们报告了49例患者(平均[标准误]年龄64[2]岁)PEG置入后的长期结局和并发症发生率,这些患者的PEG喂养平均时长为175天(范围30 - 560天)。数据为前瞻性收集。所有病例的PEG置入在技术上均获成功,与操作相关的死亡率为2%。早期(<30天)死亡率和发病率分别为8%和22%。在存活超过30天的45例患者中,76%能够回家,6例患者最终能够恢复经口进食。有27例晚期并发症:2例造口部位感染、17例机械性问题和8例胃肠功能障碍发作。51%的患者完全没有问题,22%的患者有2种或更多并发症。47%的并发症需要住院治疗才能解决。PEG长期肠内喂养安全、有效,并发症发生率低。我们的患者由专业营养团队管理,这一政策可能会降低在家接受喂养患者的并发症发生率和住院次数,并使吞咽困难患者能够早期出院,从而降低成本。