Stamm M, Sorg I
Institut für Veterinärbakteriologie, Universität Zürch.
Schweiz Arch Tierheilkd. 1993;135(3):89-95.
This review describes the mechanism of intestinal colonization by enterotoxigenic and enterotoxaemic Escherichia (E.) coli in swine. Colonization depends on specific binding between adhesive fimbriae and receptors on the enterocytes. Special focus is given on the occurrence of specific intestinal receptors for the fimbrial antigens F4 (K88), F5 (K99), F6 (987P) and F41. The demonstration of these receptors allows the identification of susceptible and resistant pigs. Furthermore unclassified adhesive fimbriae of E. coli isolated from pigs with postweaning diarrhea and edema disease are described. Finally the present knowledge is discussed in context with protection of animals against infections.
本综述描述了产肠毒素和肠毒血症大肠杆菌在猪肠道内定植的机制。定植取决于黏附菌毛与肠上皮细胞上受体之间的特异性结合。重点关注了菌毛抗原F4（K88）、F5（K99）、F6（987P）和F41特异性肠道受体的存在情况。这些受体的证实有助于识别易感猪和抗性猪。此外，还描述了从断奶后腹泻和水肿病猪中分离出的未分类大肠杆菌黏附菌毛。最后，结合动物抗感染保护对现有知识进行了讨论。
