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用于造血干细胞移植的脐血库:国际脐血移植登记处

Cord blood banking for hematopoietic stem cell transplantation: an international cord blood transplant registry.

作者信息

Gluckman E, Wagner J, Hows J, Kernan N, Bradley B, Broxmeyer H E

机构信息

Bone Marrow Transplant Unit, Hopital Saint Louis, Paris, France.

出版信息

Bone Marrow Transplant. 1993 Mar;11(3):199-200.

PMID:8096776
Abstract

Human umbilical cord blood contains enough hematopoietic stem cells for transplantation instead of marrow cells to cure children and adults with leukemia and other potentially fatal marrow disorders. An international cord blood transplantation registry is currently collecting information about the results of these transplants. As a result of relative immune deficiency at birth, it is likely that partially matched unrelated transplants can be successful; for this purpose an international cord blood banking project is described.

摘要

人类脐带血含有足够用于移植的造血干细胞,可替代骨髓细胞来治疗患有白血病和其他潜在致命性骨髓疾病的儿童及成人。一个国际脐带血移植登记处目前正在收集这些移植结果的相关信息。由于出生时相对的免疫缺陷,部分匹配的非亲属移植很可能会成功;为此描述了一个国际脐带血库项目。

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