Chang Y, Kargas S A, Goates J J, Horoupian D S
Department of Pathology, Stanford University Medical Center, CA 94305.
Clin Neuropathol. 1993 Mar-Apr;12(2):84-7.
Neurologic symptoms are common in patients with the Churg-Strauss syndrome and often manifest as a peripheral neuropathy of the mononeuritis multiplex type secondary to vasculitis. Reports of central nervous system involvement is less frequent and ranges from psychiatric disturbances to cerebral hemorrhage. We report the first case of pathologically documented vasculitis involving the choroid plexus causing massive and fatal intraventricular and subarachnoid hemorrhages in a 47-year-old patient with Churg-Strauss syndrome.
神经系统症状在Churg-Strauss综合征患者中很常见,常表现为继发于血管炎的多发性单神经炎型周围神经病变。中枢神经系统受累的报道较少,范围从精神障碍到脑出血。我们报告了首例经病理证实的血管炎累及脉络丛,导致一名47岁Churg-Strauss综合征患者发生大量致命性脑室内和蛛网膜下腔出血的病例。