Histone-produced magnesium extrusion from mitochondria and magnesium binding to histone.
作者信息
Hillar M, Chambers D
出版信息
Arch Int Physiol Biochim. 1978 May;86(2):235-41. doi: 10.3109/13813457809069900.
PMID:80980
Abstract
Histone (60 microgram/mg mit. protein) extrudes Mg2+ from mitochondria by 30% with the utilization of endogenous substrates; in the presence of rotenone extrusion drops to about 18%. Dinitrophenol and ADP prevent this effect of histone. Mg2+ extrusion produced by histone depends on histone concentration being at a maximum (100% extrusion) at 107 microgram histone/mit. protein. It was found also that histone alone binds Mg2+ (1.6 nmol Mg2+/microgram histone).
摘要
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