雌激素对心血管的保护作用——一种钙拮抗剂效应？
Cardiovascular protection by oestrogen--a calcium antagonist effect?
作者信息
Collins P, Rosano G M, Jiang C, Lindsay D, Sarrel P M, Poole-Wilson P A
机构信息
Department of Cardiac Medicine, National Heart and Lung Institute, London, UK.
出版信息
Lancet. 1993 May 15;341(8855):1264-5. doi: 10.1016/0140-6736(93)91158-i.
PMID:8098404
Abstract
During their premenopausal years, women have a lower risk than men of getting cardiovascular disease. This protection continues after the menopause if women receive oestrogen replacement. Based on new experimental evidence we propose that some of the cardiovascular benefits of oestrogen replacement therapy may be due to a long-term calcium antagonist effect of oestrogen.
摘要
在绝经前的岁月里，女性患心血管疾病的风险低于男性。如果女性接受雌激素替代治疗，这种保护作用在绝经后仍会持续。基于新的实验证据，我们提出雌激素替代疗法的一些心血管益处可能归因于雌激素的长期钙拮抗剂作用。
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