Rosenberg R
Institut for psykiatrisk grundforskning, Psykiatrisk Hospital, Universitetets hospital i Arhus, Risskov.
Nord Med. 1993;108(5):139-44.
In recent years, research into biological aspects of psychiatric disorders has had high priority. Biological psychiatry, or neuropsychiatry, is characterised by (a) empiricist epistemology, (b) a diathesis-stress disease model, (c) neurobiological pathogenetic theories, (d) chemical or physical treatment as an essential though not necessarily sufficient measure, and (e) a patient-oriented ethical approach. A short review of some major topics is given, including standardised assessment, clinical and molecular genetics, neurotransmitter theories, neuro-imaging techniques, panic disorder, classic and novel psychopharmacological compounds, and alcohol and drug dependence. Avenues of future research endeavours are delineated, and it is concluded that in the future neuropsychiatry should play a major part in psychiatry, though closely integrated with psychological and social theory.
近年来,对精神障碍生物学方面的研究一直占据着优先地位。生物精神病学,即神经精神病学,具有以下特点:(a)经验主义认识论;(b)素质-应激疾病模型;(c)神经生物学发病机制理论;(d)化学或物理治疗作为一项必要但不一定充分的措施;以及(e)以患者为导向的伦理方法。本文简要回顾了一些主要主题,包括标准化评估、临床和分子遗传学、神经递质理论、神经成像技术、惊恐障碍、经典和新型精神药物化合物,以及酒精和药物依赖。文中还描绘了未来研究努力的方向,并得出结论:未来神经精神病学应在精神病学中发挥重要作用,尽管要与心理和社会理论紧密结合。