造血干细胞的异质性。
Heterogeneity of hematopoietic stem cells.
作者信息
Uchida N, Fleming W H, Alpern E J, Weissman I L
机构信息
Department of Pathology, Stanford University School of Medicine, California 94305.
出版信息
Curr Opin Immunol. 1993 Apr;5(2):177-84. doi: 10.1016/0952-7915(93)90002-a.
PMID:8099486
Abstract
Hematopoietic stem cells are capable of multi-lineage differentiation to all blood cell types as well as self-renewal and radioprotection. Thy-1.1lo Lin-/lo Sca-1+ cells are a heterogeneous mixture of quiescent and self-renewing hematopoietic stem cells as well as multi-lineage expanding cells.
摘要
造血干细胞能够多谱系分化为所有血细胞类型，同时具备自我更新和辐射防护能力。Thy-1.1lo Lin-/lo Sca-1+细胞是静止和自我更新的造血干细胞以及多谱系扩增细胞的异质混合物。
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