Sussman N
Department of Psychiatry, New York University Medical Center, N.Y.
J Clin Psychiatry. 1993 May;54 Suppl:44-51.
Anxiety is common and often disabling. Although effective treatments are available, the use of antianxiety medication remains controversial. Some of the controversy involves the relative benefits of psychological versus pharmacologic interventions. Much of the expressed concern, however, relates to the risks of abuse and dependence associated with standard antianxiety drugs. In some instances, concern about these risks prevents patients from receiving potentially effective treatment. In other instances, failure to recognize possible abuse and dependence results in a clinical dilemma. This presentation will address the factors involved in anxiolytic drug dependence and abuse, including patient characteristics and the pharmacologic profiles of anxiolytic drugs. Specific recommendations about how to minimize abuse and dependence through such measures as diagnostic assessment, patient education, drug selection, and treatment planning will be offered.
焦虑很常见,且常常使人丧失能力。尽管有有效的治疗方法,但抗焦虑药物的使用仍存在争议。部分争议涉及心理干预与药物干预的相对益处。然而,大部分表达的担忧与标准抗焦虑药物相关的滥用和依赖风险有关。在某些情况下,对这些风险的担忧使患者无法接受可能有效的治疗。在其他情况下,未能认识到可能的滥用和依赖会导致临床困境。本报告将探讨抗焦虑药物依赖和滥用所涉及的因素,包括患者特征和抗焦虑药物的药理学特征。还将提供关于如何通过诊断评估、患者教育、药物选择和治疗规划等措施将滥用和依赖降至最低的具体建议。