Berardi R R, Dunn-Kucharski V A
University of Michigan Medical Center, Ann Arbor.
Am Pharm. 1993 Jun;NS33(6):26-34. doi: 10.1016/s0160-3450(15)30757-1.
Peptic ulcers can develop when there is an imbalance between gastric acid secretion and gastroduodenal mucosal defense. Investigators are looking at the role of Helicobacter pylori in the development of peptic ulcer disease; eradication of the microorganism may reduce recurrence. Approved drug therapy includes H2-receptor antagonists, omeprazole, sucralfate, and antacids. Recommendations for treating and counseling patients are provided.
当胃酸分泌与胃十二指肠黏膜防御之间出现失衡时，就会发生消化性溃疡。研究人员正在研究幽门螺杆菌在消化性溃疡疾病发展中的作用；根除这种微生物可能会降低复发率。批准的药物治疗包括H2受体拮抗剂、奥美拉唑、硫糖铝和抗酸剂。文中还提供了治疗和咨询患者的建议。
