Grisk O, Küster U, Ansorge S
Klinik für Innere Medizin, Medizinische Akademie Magdeburg.
Biol Chem Hoppe Seyler. 1993 Apr;374(4):287-90. doi: 10.1515/bchm3.1993.374.1-6.287.
The activity of gamma-glutamyl transpeptidase (EC 2.3.2.2) was observed in populations of non-stimulated mononuclear cells of human peripheral blood selected with antibody-coated magnetic particles. The highest activities of gamma-GT were found in monocytes (7.3-20.0 pkat/10(6) cells). The examination of T lymphocytes revealed a significant difference between CD4-positive (4.1 pkat/10(6) cells) and CD8-positive cells (1.2 pkat/10(6) cells). B lymphocytes and NK cells showed the lowest activities of 0.3 and 1.3 pkat/10(6) cells, respectively. The obvious differences in gamma-GT activities demonstrated here may reflect different biochemical capacities of these cell types, related to their distinct functions in the immune system.
在用抗体包被的磁性颗粒筛选的人外周血未刺激单核细胞群体中观察到γ-谷氨酰转肽酶（EC 2.3.2.2）的活性。γ-GT的最高活性见于单核细胞（7.3 - 20.0 pkat/10⁶ 个细胞）。对T淋巴细胞的检测显示，CD4阳性细胞（4.1 pkat/10⁶ 个细胞）和CD8阳性细胞（1.2 pkat/10⁶ 个细胞）之间存在显著差异。B淋巴细胞和NK细胞的活性最低，分别为0.3和1.3 pkat/10⁶ 个细胞。此处显示的γ-GT活性的明显差异可能反映了这些细胞类型不同的生化能力，这与它们在免疫系统中的不同功能相关。
