Giudicelli J, Philip P J, Delque P, Ayraud N, Sudaka P
Clin Chim Acta. 1983 May 30;130(2):149-53. doi: 10.1016/0009-8981(83)90111-0.
Neutral maltase activity has been determined in purified monocytes, T and B lymphocytes from human peripheral blood and major lymphoid organs. In peripheral blood as in all lymphoid organs studied, neutral maltase activity was found to be significantly higher in monocytes than in B lymphocytes. Neutral maltase activity was never detected in T lymphocytes whatever the methods used for their purification. Furthermore, in each case studied, B lymphocyte fractions represented all the activities measured in unseparated lymphocytes. Neutral maltase thus appears to be the first enzymatic marker useful for the recognition and characterisation of B lymphocytes.
已测定人外周血及主要淋巴器官中纯化的单核细胞、T淋巴细胞和B淋巴细胞的中性麦芽糖酶活性。在所有研究的淋巴器官以及外周血中，单核细胞的中性麦芽糖酶活性显著高于B淋巴细胞。无论采用何种纯化方法，T淋巴细胞中均未检测到中性麦芽糖酶活性。此外，在每项研究中，B淋巴细胞组分呈现了未分离淋巴细胞中所测的全部活性。因此，中性麦芽糖酶似乎是用于识别和表征B淋巴细胞的首个酶标志物。
