Seligmann M
Br J Cancer Suppl. 1975 Mar;2:356-61.
The laboratory findings upon which the diagnosis of alpha chain disease relies and the main results of immunochemical, structural and biosynthetic studies of the pathological immunoglobulin are reviewed briefly. The pathogenesis of the disease is discussed in view of its possibly non-malignant nature at the early stage and of its peculiar geographic distribution, suggesting the triggering role of an intestinal micro-organism.
简要回顾了α链病诊断所依据的实验室检查结果以及病理性免疫球蛋白的免疫化学、结构和生物合成研究的主要结果。鉴于该病早期可能具有的非恶性性质及其独特的地理分布，讨论了其发病机制，提示肠道微生物具有触发作用。
