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[使用球囊导管对胸廓内动脉移植物进行机械扩张]

[Mechanical dilation of the internal thoracic artery graft by using balloon catheter].

作者信息

Yamaguchi A, Kitamura N, Miki T, Koh Y, Kawashima M, Shuntoh K, Kimura S

机构信息

Department of Cardiovascular Surgery, Osaka National Hospital, Japan.

出版信息

Nihon Kyobu Geka Gakkai Zasshi. 1993 Jun;41(6):1008-13.

PMID:8101554
Abstract

We evaluated the free flow of the internal thoracic artery grafts (ITA) which were dilated with a balloon catheter. Further, we examined the postoperative angiographic findings and histology of the ITAs by scanning electron microscopy. In 25 patients with internal thoracic artery grafting, the artery was dilated with a balloon catheter (Fogarty IMAG kit) that was withdrawn at tensions of less than 30 gm. The mean free flow rate of the left ITAs (LITAs) increased from 64.2 ml/min to 101.9 ml/min by injection of papaverine to ITAs (p < 0.05). The mean free flow rate of the balloon dilated LITAs were 160.8 ml/min which was significantly higher when compared with that of control and papaverine (p < 0.01, p < 0.01). The mean free flow rate of the balloon dilated right ITAs (RITAs) showed 183.2 ml/min, it was significantly higher (p < 0.01, p < 0.05) compared with that of control (78.4 ml/min) and papaverine (129.2 ml/min). Irregularity was documented in 16% of the ITAs in spite of the great patency rate (100%) from the postoperative angiogram. Using scanning electron microscopy, endothelial cell borders were well demarcated in the proximal portion of the dilated ITA. However, the distal portion of the endothelium displayed gradual destruction. Although mechanical dilation of the ITA graft by balloon calibration is very effective in increasing the free flow rate of ITA, we should be prepared for the intimal damage of the ITA graft.

摘要

我们评估了用球囊导管扩张的胸廓内动脉移植物(ITA)的自由血流情况。此外,我们通过扫描电子显微镜检查了ITA术后的血管造影结果和组织学情况。在25例接受胸廓内动脉移植的患者中,使用球囊导管(Fogarty IMAG套件)在小于30克的张力下撤出对动脉进行扩张。通过向ITA注射罂粟碱,左ITA(LITA)的平均自由血流率从64.2毫升/分钟增加到101.9毫升/分钟(p<0.05)。球囊扩张的LITA的平均自由血流率为160.8毫升/分钟,与对照组和罂粟碱组相比显著更高(p<0.01,p<0.01)。球囊扩张的右ITA(RITA)的平均自由血流率为183.2毫升/分钟,与对照组(78.4毫升/分钟)和罂粟碱组(129.2毫升/分钟)相比显著更高(p<0.01,p<0.05)。尽管术后血管造影显示通畅率很高(100%),但16%的ITA存在不规则情况。使用扫描电子显微镜,在扩张的ITA近端部分内皮细胞边界清晰。然而,内皮的远端部分显示出逐渐破坏。尽管通过球囊校准对ITA移植物进行机械扩张在增加ITA的自由血流率方面非常有效,但我们应该为ITA移植物的内膜损伤做好准备。

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