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[帕金森病及抗精神病药物所致帕金森综合征的长潜伏期听觉诱发电位]

[Long-latency auditory evoked responses in Parkinson disease and in parkinsonism induced by neuroleptics].

作者信息

Jacquy J, Mettens P, Blum S, Jacqmotte N, Vanderheyden J E

机构信息

Service de Neurologie, Hôpital Civil Charleroi, Montignies-le-Tilleul.

出版信息

Acta Neurol Belg. 1993;93(3):119-29.

PMID:8102219
Abstract

The amplitude and latency of the N100 wave (auditory evoked potentials) were studied in 28 normals, 85 parkinsonians, 24 extrapyramidal syndromes induced by neuroleptics and 12 neurological control patients. The latency decreases as an inverse function of the intensity of stimulation in normals, controls, treated parkinsonians and in extrapyramidal syndrome induced by neuroleptics. Untreated parkinsonians do not show an evident relation between the latency and the stimulation level. The amplitude of the N100 decreases when neuroleptic induced parkinsonism improves.

摘要

对28名正常人、85名帕金森病患者、24名由抗精神病药物引起的锥体外系综合征患者和12名神经科对照患者研究了N100波(听觉诱发电位)的波幅和潜伏期。在正常人、对照者、接受治疗的帕金森病患者以及由抗精神病药物引起的锥体外系综合征患者中,潜伏期随刺激强度的增加呈反比下降。未经治疗的帕金森病患者的潜伏期与刺激水平之间未显示出明显关系。当抗精神病药物所致帕金森综合征改善时,N100波幅降低。

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