Almeida R, Santos M V
Serviço de Neurologia, H. Sto. António dos Capuchos, Lisboa.
Acta Med Port. 1993 Jun;6(6):239-44.
Neuroleptics are drugs frequently used in clinical psychiatric and neurologic daily practice. They share the ability to block postsynaptic dopamine D2 receptors in the Central Nervous System. Their potency is directly proportional to that block. Movement disorders are the most frequent and important adverse effects induced by these antipsychotic drugs. This work will highlight some of the essential aspects of distinct neuroleptic-induced movement disorders.
抗精神病药物是临床精神科和神经科日常实践中常用的药物。它们都具有阻断中枢神经系统突触后多巴胺D2受体的能力。其效力与这种阻断作用成正比。运动障碍是这些抗精神病药物引起的最常见且最重要的不良反应。这项工作将重点介绍不同抗精神病药物所致运动障碍的一些基本方面。
