Nicassio P M, Radojevic V, Weisman M H, Culbertson A L, Lewis C, Clemmey P
Department of Medicine, University of California, San Diego (UCSD), School of Medicine.
J Rheumatol. 1993 Jul;20(7):1114-20.
Fifty patients with rheumatoid arthritis participated in an assessment of their helplessness before and after a 3-month disease modifying drug trial. A multidimensional approach measuring helplessness was used, assessing cognitive, affective, and behavioral components. Both before and after the drug trial, helplessness indices accounted for a highly significant amount of variation in self-reported pain and functional disability. Moreover, Time 1 helplessness predicted greater flare activity after the drug trial. Helplessness indices, however, did not correlate with joint examination measures within time periods, nor did they predict change in these measures over the drug trial. The importance of the role of helplessness in subjective and objective measures of clinical status in persons undergoing drug therapy is discussed.
50名类风湿性关节炎患者参与了一项在为期3个月的病情缓解药物试验前后对其无助感的评估。采用了一种测量无助感的多维度方法，评估认知、情感和行为成分。在药物试验前后，无助感指数在自我报告的疼痛和功能残疾方面解释了很大一部分变异。此外，试验前的无助感预示着药物试验后有更大的病情发作活动。然而，无助感指数在各时间段内与关节检查指标不相关，也不能预测药物试验期间这些指标的变化。本文讨论了无助感在接受药物治疗的患者临床状态主观和客观测量中的作用的重要性。
