Metabolism of strychnine N-oxide and brucine N-oxide by human intestinal bacteria.
作者信息
el-Mekkawy S, Meselhy M R, Kawata Y, Kadota S, Hattori M, Namba T
机构信息
Research Institute for Wakan-Yaku (Traditional Sino-Japanese Medicines), Toyama Medical and Pharmaceutical University.
出版信息
Planta Med. 1993 Aug;59(4):347-50. doi: 10.1055/s-2006-959698.
PMID:8103941
Abstract
Anaerobic incubation of strychnine N-oxide with human intestinal bacteria resulted in its transformation to strychnine and 16-hydroxystrychnine. Similarly, brucine N-oxide was transformed to brucine and 16-hydroxybrucine.
摘要
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