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创伤后时期血浆中的游离氨基酸

Free amino acids in plasma in the post-traumatic period.

作者信息

Dölp R, Fekl W, Ahnefeld W

出版信息

Infusionsther Klin Ernahr. 1975 Oct;2(5):321-4. doi: 10.1159/000219644.

DOI:10.1159/000219644
PMID:810434
Abstract

The pattern of the amino acids in plasma of 22 polytraumatized patients who obtained a standardized total parenteral nutrition over a period of 3-10 days was studied. Following to the trauma - before the infusion period - a rapid decrease of concentration of a part of the amino acids appeared. During the period of parenteral nutrition nearly all of the amino acids showed a different increase in plasma, partly manifold over their normal range which resulted in a disturbance of the pattern of the amino acids. Particularly the influence of the infusion therapy on the sulfur-containing amino acids, the branched-chain amino acids and the glycine level in plasma is discussed.

摘要

对22名多发伤患者进行了研究,这些患者在3 - 10天内接受了标准化的全胃肠外营养,研究了其血浆中氨基酸的模式。创伤后——在输注期之前——部分氨基酸浓度迅速下降。在胃肠外营养期间,几乎所有氨基酸在血浆中的含量都有不同程度的升高,部分升高幅度超过正常范围,导致氨基酸模式紊乱。特别讨论了输注疗法对血浆中含硫氨基酸、支链氨基酸和甘氨酸水平的影响。

相似文献

1
Free amino acids in plasma in the post-traumatic period.创伤后时期血浆中的游离氨基酸
Infusionsther Klin Ernahr. 1975 Oct;2(5):321-4. doi: 10.1159/000219644.
2
Partial substitution of amino acids of a parenteral solution with tripeptides: effects on parameters of protein nutrition in baboons.用三肽部分替代肠外营养液中的氨基酸:对狒狒蛋白质营养参数的影响
Metabolism. 1984 May;33(5):420-4. doi: 10.1016/0026-0495(84)90140-9.
3
[Reduced parenteral calorie administration after severe multiple injuries].[严重多发伤后肠外热量供给减少]
Anaesthesist. 1983 Nov;32(11):548-53.
4
Use of selected visceral protein measurements in the comparison of branched-chain amino acids with standard amino acids in parenteral nutrition support of injured patients.在创伤患者肠外营养支持中,使用选定的内脏蛋白测量值比较支链氨基酸与标准氨基酸。
Surgery. 1990 May;107(5):503-10.
5
Deca-Durabolin and parenteral nutrition in post-traumatic patients.创伤后患者使用癸酸诺龙与肠外营养
Acta Endocrinol Suppl (Copenh). 1985;271:60-9. doi: 10.1530/acta.0.109s0060.
6
[Nutritional and metabolic aspects of the therapy of major trauma].
Minerva Dietol Gastroenterol. 1981 Apr-Jun;27(2):223-84.
7
[Behavior of free amino acids in plasma and urine of intensive care patients with multiple injuries during the administration of an amino acid solution with 10% branched-chain amino acids].
Infusionsther Klin Ernahr. 1981 Oct;8(5):244-52.
8
The role of the branched-chain amino acids in decreasing muscle catabolism in vivo.支链氨基酸在体内减少肌肉分解代谢中的作用。
Surgery. 1978 Jun;83(6):611-8.
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Biochemical changes associated with severe trauma.
Am J Clin Nutr. 1980 Oct;33(10):2119-27. doi: 10.1093/ajcn/33.10.2119.
10
Evaluation of an infusion solution enriched with branched chain amino acid in parenteral nutrition of rats.富含支链氨基酸的输注溶液在大鼠肠外营养中的评价
J Nutr. 1980 Apr;110(4):710-9. doi: 10.1093/jn/110.4.710.

引用本文的文献

1
Effect of the route of nutrition and L-alanyl-L-glutamine supplementation in amino acids' concentration in trauma patients.营养途径及补充L-丙氨酰-L-谷氨酰胺对创伤患者氨基酸浓度的影响。
Eur J Trauma Emerg Surg. 2018 Dec;44(6):869-876. doi: 10.1007/s00068-017-0851-1. Epub 2017 Oct 4.
2
[Plasma amino acid concentrations and isoleucine-phenylalanine quotient in patients with acute myocardial infarct during amino acid infusion].急性心肌梗死患者氨基酸输注期间的血浆氨基酸浓度及异亮氨酸-苯丙氨酸比值
Med Klin (Munich). 1997 Jul 15;92(7):376-80. doi: 10.1007/BF03042566.
3
[Alanine as a nitrogen sparing and gluconeogenetic substrate in the postoperative state (author's transl)].
丙氨酸作为术后状态下的氮节约和糖异生底物(作者译)
Klin Wochenschr. 1981 Jul 15;59(14):797-802. doi: 10.1007/BF01724686.
4
Nutritional support of the multiple trauma patient.
World J Surg. 1983 Jan;7(1):132-42. doi: 10.1007/BF01655921.
5
Protein and amino acid metabolism after severe cerebral trauma.
Intensive Care Med. 1985;11(4):192-8. doi: 10.1007/BF00272402.