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一名接触被2,3,7,8-四氯二苯并对二恶英污染的废油的工人患血管肉瘤、迟发性皮肤卟啉病及可能的氯痤疮。

Angiosarcoma, porphyria cutanea tarda, and probable chloracne in a worker exposed to waste oil contaminated with 2,3,7,8-tetrachlorodibenzo-p-dioxin.

作者信息

McConnell R, Anderson K, Russell W, Anderson K E, Clapp R, Silbergeld E K, Landrigan P J

机构信息

Division of Environmental and Occupational Medicine, Mount Sinai School of Medicine, New York 10029.

出版信息

Br J Ind Med. 1993 Aug;50(8):699-703. doi: 10.1136/oem.50.8.699.

Abstract

A worker developed angiosarcoma, porphyria cutanea tarda, and skin lesions characteristic of mild chloracne. About 10 years earlier he had been employed at a truck terminal in Saint Louis, Missouri, at a time when it was sprayed with waste oil contaminated with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). The occurrence of these three rare conditions in a single exposed worker supports the aetiological relation between environmental exposure to TCDD and the subsequent development of soft tissue sarcoma and porphyria cutanea tarda.

摘要

一名工人患上了血管肉瘤、迟发性皮肤卟啉病以及具有轻度氯痤疮特征的皮肤病变。大约10年前,他受雇于密苏里州圣路易斯的一个卡车终点站,当时该终点站被含有2,3,7,8 - 四氯二苯并对二恶英(TCDD)的废油喷洒过。在一名受暴露工人身上出现这三种罕见病症,支持了环境暴露于TCDD与随后发生软组织肉瘤和迟发性皮肤卟啉病之间的病因关系。

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本文引用的文献

1
INDUSTRIALLY ACQUIRED PORPHYRIA.工业性获得性卟啉病
Arch Dermatol. 1964 Jun;89:793-7. doi: 10.1001/archderm.1964.01590300021006.
5
Porphyria turcica due to hexachlorobenzene: a 20 to 30 year follow-up study on 204 patients.
Br J Dermatol. 1984 Oct;111(4):413-22. doi: 10.1111/j.1365-2133.1984.tb06603.x.

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