Ward J R, Cottrell S, Thomas H J, Jones T A, Howe C M, Hampton G M, Deaven L, Sheer D, Bodmer W F, Solomon E
Molecular Analysis of Mammalian Mutation Laboratory, Imperial Cancer Research Fund, Lincoln's Inn Fields, London, United Kingdom.
Genomics. 1993 Jul;17(1):15-24. doi: 10.1006/geno.1993.1277.
A long-range restriction map encompassing the APC (adenomatous polyposis coli) gene has been constructed. The map includes 35 DNA markers and consists of two segments of 10 and 2.5 Mb. Published genetic markers have been connected using additional, nonpolymorphic DNA probes. The map clarifies marker order and allows comparison of physical and genetic data.
构建了一个包含APC(腺瘤性息肉病 coli)基因的长程限制图谱。该图谱包括35个DNA标记,由两个分别为10 Mb和2.5 Mb的片段组成。已使用额外的非多态性DNA探针连接已发表的遗传标记。该图谱明确了标记顺序,并允许对物理数据和遗传数据进行比较。