A long-range restriction map of human chromosome 5q21-q23.

作者信息

Ward J R, Cottrell S, Thomas H J, Jones T A, Howe C M, Hampton G M, Deaven L, Sheer D, Bodmer W F, Solomon E

机构信息

Molecular Analysis of Mammalian Mutation Laboratory, Imperial Cancer Research Fund, Lincoln's Inn Fields, London, United Kingdom.

出版信息

Genomics. 1993 Jul;17(1):15-24. doi: 10.1006/geno.1993.1277.

A long-range restriction map encompassing the APC (adenomatous polyposis coli) gene has been constructed. The map includes 35 DNA markers and consists of two segments of 10 and 2.5 Mb. Published genetic markers have been connected using additional, nonpolymorphic DNA probes. The map clarifies marker order and allows comparison of physical and genetic data.