Kunishio K, Kawada S, Matsuhisa T, Moriyama E, Norikane H, Matsumoto Y, Fujita H
Department of Neurosurgery, Kagawa Prefectural Central Hospital.
Noshuyo Byori. 1993;10(1):81-6.
A case of choroid plexus papilloma (CPP) associated with overproduction of cerebrospinal fluid (CSF) in an infant is reported. The tumor was totally resected. Histologically, it was diagnosed as CPP with several mitosis, however, there were no other features indicating malignancy. Transthyretin immunoreactivity was found in the tumor cells on CSF cytological examination as well as in surgical specimens. Though the percentage of PCNA was high (10.8%), it was not higher than other benign CPPs (mean score: 18.2%). There was no recurrence or dissemination on follow-up CT or MRI 1 year after surgery. The patient has grown normally after surgery without a shunting procedure.
报告了一例婴儿脉络丛乳头状瘤（CPP）合并脑脊液（CSF）过度产生的病例。肿瘤被完全切除。组织学上，其被诊断为有多个核分裂象的CPP，但没有其他提示恶性的特征。在脑脊液细胞学检查以及手术标本中，肿瘤细胞发现有转甲状腺素蛋白免疫反应性。虽然增殖细胞核抗原（PCNA）的百分比很高（10.8%），但并不高于其他良性CPP（平均得分：18.2%）。术后1年的随访CT或MRI检查未发现复发或播散。患者术后生长正常，无需分流手术。
