Cartier R, Cartier P, Fontaine A
Division of Cardiovascular Surgery, Montreal Heart Institute, Que.
Can J Surg. 1993 Oct;36(5):411-6.
To validate the use of Doppler ultrasonography and duplex scanning as the only means of preoperative assessment in carotid disease.
A retrospective study performed between January 1980 and December 1989.
Of 597 carotid endarterectomies carried out by one author, 130 procedures were performed on 118 patients (47 women, 71 men, ranging in age from 49 to 85 years) without preoperative cerebral angiography. Justifications for proceeding without angiography were risk of angiography (27 patients), iodine allergy (8 patients), renal insufficiency (5 patients), technical problems (4 patients) and surgeon's preference (74 patients).
Doppler ultrasonography and duplex scanning were the only means of preoperative assessment on 130 occasions. The studies were done by fully trained radiologists. Until 1982 carotid stenosis was assessed with a continuous wave bidirectional Doppler flowmeter and gray-scale ultrasonography in equivocal cases. Thereafter, a real-time spectrum analyser connected on-line to a Doppler flowmeter was used. Duplex scanning was introduced in 1985.
Surgical observations confirmed the preoperative assessment on 124 occasions (96%).
Six patients had occlusion of the internal carotid artery (ICA); five patients had recent thrombosis that had occurred between the noninvasive assessment and the endarterectomy. Revascularization was successful in all. In one patient, the ICA was chronically occluded. In 63 patients, the mean pressure in the ICA stump and the mean gradient across the stenosis, measured intraoperatively, were 40 +/- 3 mm Hg (95% confidence interval: 34 to 48 mm Hg) and 55 +/- 3 mm Hg (95% confidence interval: 46 to 58 mm Hg), respectively, which confirmed the severity of the stenosis.
The authors conclude that in their institution, carotid endarterectomy based on Doppler ultrasonography and duplex scanning only is reliable and safe.
验证将多普勒超声检查和双功扫描作为颈动脉疾病术前评估的唯一手段的应用价值。
1980年1月至1989年12月间进行的一项回顾性研究。
在一位作者实施的597例颈动脉内膜切除术患者中,118例患者(47名女性,71名男性,年龄49至85岁)在未进行术前脑血管造影的情况下接受了130例手术。未进行血管造影的理由包括血管造影风险(27例患者)、碘过敏(8例患者)、肾功能不全(5例患者)、技术问题(4例患者)以及外科医生的偏好(74例患者)。
在130例手术中,多普勒超声检查和双功扫描是术前评估的唯一手段。这些检查由训练有素的放射科医生完成。1982年以前,在可疑病例中使用连续波双向多普勒流量计和灰阶超声评估颈动脉狭窄。此后,使用与多普勒流量计在线连接的实时频谱分析仪。双功扫描于1985年引入。
手术观察在124例(96%)中证实了术前评估。
6例患者颈内动脉(ICA)闭塞;5例患者在无创评估和内膜切除术之间发生了近期血栓形成。所有患者血管重建均成功。1例患者ICA慢性闭塞。在63例患者中,术中测量的ICA残端平均压力和狭窄处平均压差分别为40±3 mmHg(95%置信区间:34至48 mmHg)和55±3 mmHg(95%置信区间:46至58 mmHg),证实了狭窄的严重程度。
作者得出结论,在他们的机构中,仅基于多普勒超声检查和双功扫描的颈动脉内膜切除术是可靠且安全的。