Ranger W R, Glover J L, Bendick P J
William Beaumont Hospital, Royal Oak, MI 48073, USA.
Am Surg. 1995 Jul;61(7):548-54; discussion 554-5.
Recent studies have suggested that carotid endarterectomy can be performed safely based solely on the noninvasive duplex ultrasound evaluation in selected patients. We have prospectively evaluated 60 consecutive patients who underwent 65 carotid endarterectomies, 48 patients without preoperative angiography and 12 with angiography. Forty-two patients were operated on for symptomatic disease, and 23 procedures were done for critical, asymptomatic stenoses. Long term followup consisted of physical examination and serial duplex scans every 3-6 months postoperatively over a mean followup period of 2.4 years. Clinical management indicated by duplex ultrasound was altered in only one of the 12 patients who had preoperative angiography, a change in the timing of the endarterectomy in a symptomatic patient with an ulcerated lesion seen at angiography. At operation the severity of disease predicted by duplex ultrasound was confirmed in all cases (100 per cent sensitivity), including one > 80% diameter stenosis interpreted by angiography as occluded; no unsuspected anatomic anomalies were found at surgery. The duplex scan also correlated well with intraoperative findings of surface ulceration and gross intraplaque hemorrhage. There was one intraoperative stroke with good recovery in a patient with preoperative angiography; and there were no deaths, for a combined morbidity and mortality of 1.6 per cent. During long term followup, 97 per cent of patients have remained symptom-free. We conclude that clinical assessment with a preoperative duplex ultrasound scan of good technical quality and interpreted in collaboration with the vascular surgeon provides appropriate information on which to base carotid endarterectomy and allows a safe alternative to the routine use of preoperative angiography.(ABSTRACT TRUNCATED AT 250 WORDS)
近期研究表明,在部分特定患者中,仅基于无创双功超声评估即可安全地实施颈动脉内膜切除术。我们前瞻性地评估了连续60例接受65次颈动脉内膜切除术的患者,其中48例未进行术前血管造影,12例进行了血管造影。42例患者因有症状疾病接受手术,23例手术针对严重的无症状狭窄。长期随访包括体格检查以及术后每3 - 6个月进行的系列双功超声扫描,平均随访期为2.4年。在12例进行了术前血管造影的患者中,只有1例根据双功超声的临床管理发生了改变,这是一名有症状患者,血管造影显示有溃疡病变,其内膜切除术的时间安排有所变化。手术时,双功超声预测的疾病严重程度在所有病例中均得到证实(敏感性100%),包括1例直径狭窄>80%的病例,血管造影显示为闭塞;手术中未发现意外的解剖异常。双功扫描还与术中表面溃疡和斑块内大量出血的发现密切相关。1例进行了术前血管造影的患者术中发生卒中,但恢复良好;无死亡病例,总的发病率和死亡率为1.6%。在长期随访期间,97%的患者无症状。我们得出结论,术前进行技术质量良好的双功超声扫描并与血管外科医生协作解读,可为颈动脉内膜切除术提供合适的依据信息,并为常规使用术前血管造影提供安全的替代方案。(摘要截选至250字)