[氯化铊-201在甲状旁腺功能亢进患者甲状旁腺诊断中的临床应用]
[Clinical utility of thallium-201 chloride in the diagnosis of parathyroid glands in patients with hyperparathyroidism].
作者信息
Fukuchi M, Suehiro M, Kusakabe K, Maki M, Ohtsuka N, Katagiri M, Torizuka K
机构信息
Department of Nuclear Medicine, Hyogo College of Medicine, Japan.
出版信息
Kaku Igaku. 1993 Dec;30(12):1481-90.
Clinical utility for detection of hyperfunctioning parathyroid glands in patients with primary and secondary hyperparathyroidism (PHPT, SHPT) using 201TlCl and 99mTcO4-images was estimated in 50 patients including 18 PHPT and 32 SHPT (male; n = 31, female; n = 19, 51.5 +/- 11.1 yr). Detection of 94 hyperfunctioning parathyroid glands in 34 cases were achieved correctly by 201TlCl and 99mTcO4- images in agreement with surgical findings. Detectability of hyperfunctioning parathyroid glands was 100% in more than 1.0 g, 62.0% in more than 0.5 g and 41.5% in less than 0.5 g respectively. Ectopic parathyroid glands in two cases and a metastasis to pretracheal lymph node in one case were clearly demonstrated. Our results show that parathyroid scintigraphy using 201TlCl and 99mTcO4- as well as 131I or 123I is useful and safe method for preoperative detection of hyperfunctioning parathyroid glands.
对50例患者（包括18例原发性甲状旁腺功能亢进症（PHPT）和32例继发性甲状旁腺功能亢进症（SHPT），男性31例，女性19例，年龄51.5±11.1岁），评估了使用201TlCl和99mTcO4图像检测原发性和继发性甲状旁腺功能亢进症（PHPT、SHPT）患者中功能亢进甲状旁腺的临床效用。在34例病例中，通过201TlCl和99mTcO4图像正确检测出94个功能亢进的甲状旁腺，与手术结果一致。功能亢进甲状旁腺的可检测性在大于1.0g时为100%，在大于0.5g时为62.0%，在小于0.5g时为41.5%。清楚显示了2例异位甲状旁腺和1例气管前淋巴结转移。我们的结果表明，使用201TlCl和99mTcO4以及131I或123I的甲状旁腺闪烁扫描术是术前检测功能亢进甲状旁腺的有用且安全的方法。
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