von Cramon D Y, Markowitsch H J, Schuri U
City Hospital Munich-Bogenhausen, Germany.
Neuropsychologia. 1993 Nov;31(11):1159-80. doi: 10.1016/0028-3932(93)90065-8.
A particularly well-documented, intelligent patient (H.I.) with very selective, minute, but most likely bilateral damage of the basal forebrain including the septal region is presented. Though behavioral progress was found for a number of areas, she remained deficient, especially in long-term memory. The severest and largely modality-nonspecific deficits were observed in recall (as opposed to recognition) situations. As a peculiar finding which we would attribute to septal damage, H.I. was mainly affected in tests containing emotional (especially emotionally negative) stimuli, or certain flavours. While this involvement might have helped her in memorizing material judged as positive, it was of negative influence under other circumstances. The septal area may serve as an interface contributing a specific combination of emotional flavour and evaluating (feedback) judgement to a larger (septo-hippocampal-amygdalar) memory and learning processing network.
本文介绍了一位记录详实、聪明的患者（H.I.），其基底前脑包括隔区存在非常选择性、微小但很可能是双侧性的损伤。尽管在多个方面发现了行为进展，但她仍有缺陷，尤其是在长期记忆方面。在回忆（与识别相对）情况下观察到最严重且在很大程度上不具有模态特异性的缺陷。作为我们认为归因于隔区损伤的一个特殊发现，H.I.在包含情感（尤其是负面情感）刺激或某些味道的测试中受到的影响最大。虽然这种影响可能在帮助她记忆被判定为积极的材料方面有作用，但在其他情况下则产生负面影响。隔区可能作为一个接口，为更大的（隔区 - 海马体 - 杏仁核）记忆和学习处理网络贡献情感味道和评估（反馈）判断的特定组合。
