Nomura M, Takeshita G, Katada K, Nakamura M, Kizukuri T, Ogura Y, Anno H, Koga S
Department of Radiology, Fujita Health University School of Medicine.
Nihon Igaku Hoshasen Gakkai Zasshi. 1993 Dec 25;53(12):1387-91.
We experienced a case of serious adverse reaction following the administration of Gd-DTPA (gadolinium with diethylenetriamine pentaacetic acid). The patient showed sneezing and hoarseness when Gd-DTPA was administered for the first time. At the second injection, when hydrocortisone was used in advance to prevent allergic reaction, she lapsed into a pre-shock state and anaphylactic reaction was strongly suggested by the laboratory data. The possibility that Gd-DTPA may cause the severe side effects must be noted.
我们遇到了一例使用钆喷酸葡胺（钆与二乙烯三胺五乙酸）后出现严重不良反应的病例。首次使用钆喷酸葡胺时，患者出现了打喷嚏和声音嘶哑。第二次注射时，预先使用氢化可的松以预防过敏反应，此时患者陷入休克前期状态，实验室数据强烈提示发生了过敏反应。必须注意钆喷酸葡胺可能引起严重副作用的可能性。
