Pastor Valverde C, Sánchez Manzano D, Yagüe Agueda R, Gil Grande R, Gómez Pellico C
Servicio de Medicina Interna, Hospital Doce de Octubre de Madrid.
Rev Clin Esp. 1993 Dec;193(9):483-4.
We reviewed cases with Rendu-Osler disease or hereditary hemorrhagic telangiectasia (HHT) between 1976 and 1989 in our area of internal medicine. Of the ten reported cases, six presented severe iron deficiency anemia-three as a result of repeated and intense epistaxis and the rest as a result of digestive losses. The most frequent clinical manifestations were: epistaxis (80%) and the presence of characteristic mucocutaneous lesions easily explored by sight (80%). We emphasize the role of this disease as a cause of iron deficiency anemia and the importance of clinical exploration.
我们回顾了1976年至1989年间在我们内科领域患有遗传性出血性毛细血管扩张症(HHT)或朗杜-奥斯勒病的病例。在报告的10例病例中,6例出现严重缺铁性贫血,其中3例是由于反复大量鼻出血,其余是由于消化性失血。最常见的临床表现为:鼻出血(80%)以及肉眼易于发现的特征性皮肤黏膜病变(80%)。我们强调了这种疾病作为缺铁性贫血病因的作用以及临床检查的重要性。