Iushchuk N D, Frolov V M, Peresadin N A
Ter Arkh. 1993;65(11):12-5.
Acute intestinal infections (AII) are characterized by marked defects of immune homeostasis. These were not related to the disease etiology though depended on the infection severity and manifested with T-lymphopenia, reduced count of circulating T-helper cells in normal amount of T-suppressor cells. This resulted in low immunoregulatory index (CD-4/CD-8). Immunological criteria have been determined indicative of the tendency to formation of a protracted AII course and long-term persistence of the agent in the host.
急性肠道感染(AII)的特征是免疫稳态存在明显缺陷。这些缺陷与疾病病因无关,尽管取决于感染的严重程度,并表现为T淋巴细胞减少,在正常数量的T抑制细胞中循环T辅助细胞数量减少。这导致免疫调节指数(CD-4/CD-8)降低。已经确定了免疫学标准,这些标准表明了AII病程迁延以及病原体在宿主体内长期持续存在的倾向。