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视网膜毛细血管:壁细胞的体外增殖

Retinal capillaries: proliferation of mural cells in vitro.

作者信息

Buzney S M, Frank R N, Robison W G

出版信息

Science. 1975 Dec 5;190(4218):985-6. doi: 10.1126/science.810891.

DOI:10.1126/science.810891
PMID:810891
Abstract

Capillaries from bovine, monkey, and human retinas maintained in tissue culture produced a monolayer of cells. Autoradiographic and electron microscopic evidence indicated that the mural cells (intramural pericytes) were the cells that proliferated. Since intramural pericytes are damaged selectively in diabetes mellitus, their availability in culture will be useful in seeking means to control diabetic retinopathy.

摘要

在组织培养中维持的来自牛、猴和人类视网膜的毛细血管产生了单层细胞。放射自显影和电子显微镜证据表明,壁细胞(壁内周细胞)是增殖的细胞。由于壁内周细胞在糖尿病中会被选择性损伤,它们在培养中的可用性将有助于寻找控制糖尿病视网膜病变的方法。

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1
Retinal capillaries: proliferation of mural cells in vitro.视网膜毛细血管:壁细胞的体外增殖
Science. 1975 Dec 5;190(4218):985-6. doi: 10.1126/science.810891.
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Aldose reductase in retinal mural cells.视网膜壁细胞中的醛糖还原酶。
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Enhancement and inhibition of mitogenic action of insulin-like growth factor I by high glucose in cultured bovine retinal pericytes.高糖对培养的牛视网膜周细胞中胰岛素样生长因子I促有丝分裂作用的增强和抑制
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Studies on developing retinal vessels. X. Formation of the basement membrane and differentiation of intramural pericytes.视网膜血管发育研究。X. 基底膜的形成及壁内周细胞的分化。
Br J Ophthalmol. 1966 Mar;50(3):124-33. doi: 10.1136/bjo.50.3.124.
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Glaucoma, capillaries and pericytes. 2. Identification and characterization of retinal pericytes in culture.青光眼、毛细血管与周细胞。2. 培养的视网膜周细胞的鉴定与特性分析。
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Studies on diabetic retinopathy. 3. Influence of diabetes on intramural pericytes.糖尿病视网膜病变研究。3. 糖尿病对壁内周细胞的影响。
Arch Ophthalmol. 1968 Sep;80(3):332-7. doi: 10.1001/archopht.1968.00980050334007.
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VEGFR1-mediated pericyte ablation links VEGF and PlGF to cancer-associated retinopathy.VEGFR1 介导体细胞消融将 VEGF 和 PlGF 与癌症相关的视网膜病变联系起来。
Proc Natl Acad Sci U S A. 2010 Jan 12;107(2):856-61. doi: 10.1073/pnas.0911661107. Epub 2009 Dec 22.
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Attenuation of proliferation and migration of retinal pericytes in the absence of thrombospondin-1.在缺乏血小板反应蛋白-1的情况下视网膜周细胞增殖和迁移的减弱
Am J Physiol Cell Physiol. 2009 Apr;296(4):C724-34. doi: 10.1152/ajpcell.00409.2008. Epub 2009 Feb 4.
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The versatility of microvascular pericytes: from mesenchyme to smooth muscle?
微血管周细胞的多功能性:从间充质到平滑肌?
Histochemistry. 1993 Jan;99(1):1-12. doi: 10.1007/BF00268014.
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Cerebral microvessels and derived cells in tissue culture: isolation and preliminary characterization.组织培养中的脑微血管及其衍生细胞:分离与初步表征
In Vitro. 1979 Jul;15(7):473-87. doi: 10.1007/BF02618149.