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结核性脑膜炎:30年回顾

Tuberculous meningitis: a 30-year review.

作者信息

Kent S J, Crowe S M, Yung A, Lucas C R, Mijch A M

机构信息

Fairfield Infectious Diseases Hospital, Victoria, Australia.

出版信息

Clin Infect Dis. 1993 Dec;17(6):987-94. doi: 10.1093/clinids/17.6.987.

Abstract

Tuberculous meningitis remains an important illness that can be difficult to diagnose in a timely fashion and carries significant morbidity. We present a retrospective review of the cases of tuberculous meningitis diagnosed and treated at a single institution. Fifty-eight cases were identified and stratified according to stage of disease at presentation. Four patients (7%) died; three (5%) developed severe neurological sequelae. Poor outcomes were largely confined to cases presenting in an advanced stage and at the extremes of age. Corticosteroids were administered to 56 patients and may have contributed to the comparatively good outcome in these cases.

摘要

结核性脑膜炎仍然是一种重要疾病,可能难以及时诊断,且具有较高的发病率。我们对一家机构诊断和治疗的结核性脑膜炎病例进行了回顾性研究。共确定了58例病例,并根据就诊时的疾病阶段进行分层。4例患者(7%)死亡;3例(5%)出现严重神经后遗症。不良结局主要局限于晚期就诊和年龄极端的病例。56例患者接受了皮质类固醇治疗,这可能是这些病例取得相对较好结局的原因之一。

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