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Human aldehyde dehydrogenase: chromosomal assignment of the gene for the isozyme that metabolizes gamma-aminobutyraldehyde.

作者信息

McPherson J D, Wasmuth J J, Kurys G, Pietruszko R

机构信息

Department of Biological Chemistry, University of California, Irvine 92717.

出版信息

Hum Genet. 1994 Feb;93(2):211-2. doi: 10.1007/BF00210615.

DOI:10.1007/BF00210615
PMID:8112751
Abstract

A cDNA clone of the E3 isozyme of human liver aldehyde dehydrogenase consisting of a 1320-base pair (bp) coding region and a 180-bp non-coding region at the 3' end was used for chromosomal localization of the E3 gene. Using a panel of human/hamster somatic cell hybrids we have localized, the gene coding for the E3 isozyme to human chromosome 1.

摘要

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本文引用的文献

1
Human aldehyde dehydrogenase. cDNA cloning and primary structure of the enzyme that catalyzes dehydrogenation of 4-aminobutyraldehyde.人醛脱氢酶。催化4-氨基丁醛脱氢反应的酶的cDNA克隆及一级结构
Eur J Biochem. 1993 Dec 1;218(2):311-20. doi: 10.1111/j.1432-1033.1993.tb18379.x.
2
Chromosome assignment, biochemical and immunological studies on a human aldehyde dehydrogenase, ALDH3.
Ann Hum Genet. 1985 May;49(2):87-100. doi: 10.1111/j.1469-1809.1985.tb01680.x.
3
The structural gene for the mitochondrial aldehyde dehydrogenase maps to human chromosome 12.
Hum Genet. 1986 Aug;73(4):365-7. doi: 10.1007/BF00279102.
4
Chromosomal assignment of the genes for human aldehyde dehydrogenase-1 and aldehyde dehydrogenase-2.人类醛脱氢酶-1和醛脱氢酶-2基因的染色体定位
Am J Hum Genet. 1986 May;38(5):641-8.
5
Human aldehyde dehydrogenase. Purification and characterization of a third isozyme with low Km for gamma-aminobutyraldehyde.人醛脱氢酶。对γ-氨基丁醛具有低Km值的第三种同工酶的纯化与特性分析。
J Biol Chem. 1989 Mar 15;264(8):4715-21.
6
Isolation of a novel mildly repetitive DNA sequence that is predominantly located at the terminus of the short arm of chromosome 4 near the Huntington disease gene.一种新的轻度重复DNA序列的分离，该序列主要位于4号染色体短臂末端靠近亨廷顿病基因的位置。
Genomics. 1989 Oct;5(3):581-8. doi: 10.1016/0888-7543(89)90026-8.
7
Human aldehyde dehydrogenase. Activity with aldehyde metabolites of monoamines, diamines, and polyamines.人类醛脱氢酶。与单胺、二胺和多胺的醛代谢产物的活性。
J Biol Chem. 1991 Jul 15;266(20):13011-8.
8
Related subunits of NF-kappa B map to two distinct loci associated with translocations in leukemia, NFKB1 and NFKB2.核因子-κB的相关亚基定位于与白血病易位相关的两个不同基因座，即NFKB1和NFKB2。
Genomics. 1992 Jun;13(2):287-92. doi: 10.1016/0888-7543(92)90244-m.