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The structural gene for the mitochondrial aldehyde dehydrogenase maps to human chromosome 12.

作者信息

Braun T, Grzeschik K H, Bober E, Singh S, Agarwal D P, Goedde H W

出版信息

Hum Genet. 1986 Aug;73(4):365-7. doi: 10.1007/BF00279102.

DOI:10.1007/BF00279102
PMID:3017845
Abstract

A cloned 850 bp cDNA fragment corresponding to the 3'-coding part of human ALDHI-mRNA was used as a probe for the chromosomal assignment of the ALDHI gene. Southern blot analysis of human-rodent somatic cell hybrids indicates that the human ALDHI gene resides on chromosome 12.

摘要

相似文献

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引用本文的文献

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Human aldehyde dehydrogenase: chromosomal assignment of the gene for the isozyme that metabolizes gamma-aminobutyraldehyde.
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[Genetically-induced variability of alcohol metabolism and its effect on drinking behavior and predisposition to alcoholism].[酒精代谢的基因诱导变异性及其对饮酒行为和酒精中毒易感性的影响]

本文引用的文献

1
Aldehyde dehydrogenase from human liver. Primary structure of the cytoplasmic isoenzyme.来自人肝脏的醛脱氢酶。细胞质同工酶的一级结构。
Eur J Biochem. 1984 May 15;141(1):21-35. doi: 10.1111/j.1432-1033.1984.tb08150.x.
2
Biochemical genetics of aldehyde dehydrogenase isozymes in the mouse: evidence for stomach- and testis-specific isozymes.小鼠醛脱氢酶同工酶的生化遗传学：胃和睾丸特异性同工酶的证据。
Biochem Genet. 1984 Dec;22(11-12):981-95. doi: 10.1007/BF00499626.
3
The role of alcohol dehydrogenase and aldehyde dehydrogenase isozymes in alcohol metabolism, alcohol sensitivity, and alcoholism.
Z Rechtsmed. 1990;103(3):169-90. doi: 10.1007/BF00207339.
乙醇脱氢酶和乙醛脱氢酶同工酶在酒精代谢、酒精敏感性及酒精中毒中的作用。
Isozymes Curr Top Biol Med Res. 1983;8:175-93.
4
Isolation and subregional mapping of a human cDNA clone detecting a common RFLP on chromosome 12.检测12号染色体上常见限制性片段长度多态性的人类cDNA克隆的分离与亚区域定位。
Hum Genet. 1984;68(1):57-61. doi: 10.1007/BF00293873.
5
Construction of a new family of high efficiency bacterial expression vectors: identification of cDNA clones coding for human liver proteins.新型高效细菌表达载体家族的构建：编码人肝蛋白的cDNA克隆的鉴定
EMBO J. 1984 Jun;3(6):1429-34. doi: 10.1002/j.1460-2075.1984.tb01988.x.
6
Chromosome assignment, biochemical and immunological studies on a human aldehyde dehydrogenase, ALDH3.
Ann Hum Genet. 1985 May;49(2):87-100. doi: 10.1111/j.1469-1809.1985.tb01680.x.
7
Cloning of cDNAs for human aldehyde dehydrogenases 1 and 2.人类乙醛脱氢酶1和2的cDNA克隆
Proc Natl Acad Sci U S A. 1985 Jun;82(11):3771-5. doi: 10.1073/pnas.82.11.3771.
8
Two aldehyde dehydrogenases from human liver. Isolation via affinity chromatography and characterization of the isozymes.来自人肝脏的两种醛脱氢酶。通过亲和色谱法进行分离及对同工酶的特性分析。
Biochim Biophys Acta. 1977 Jul 8;483(1):35-45. doi: 10.1016/0005-2744(77)90005-5.