• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

在临床毒理学实验室对母乳进行滥用药物的常规分析。

The routine analysis of breast milk for drugs of abuse in a clinical toxicology laboratory.

作者信息

Dickson P H, Lind A, Studts P, Nipper H C, Makoid M, Therkildsen D

机构信息

Creighton University School of Medicine, Department of Pathology, Omaha, NE.

出版信息

J Forensic Sci. 1994 Jan;39(1):207-14.

PMID:8113701
Abstract

Drug screening of breast milk in a clinical toxicology laboratory is reported. Findings from three cases include cocaine, ethylbenzoylecgonine (cocaethylene), ethanol, oxycodone, codeine, and nicotine. We believe this to be the first report of ethylbenzoylecgonine in human breast milk. One other specimen submitted for analysis was screened with negative results. Screening and confirmation procedures adapted for use with breast milk are described. Finally, the potential for cocaine intoxication from mother to baby is discussed. Estimates of infant blood cocaine concentration are given which may increase awareness of the need to monitor milk and blood cocaine concentrations in the infant when the situation warrants.

摘要

报道了在临床毒理学实验室对母乳进行药物筛查的情况。三例病例的检测结果包括可卡因、乙基苯甲酰爱康宁(可口乙酮)、乙醇、羟考酮、可待因和尼古丁。我们认为这是人类母乳中出现乙基苯甲酰爱康宁的首次报道。提交分析的另一份样本筛查结果为阴性。描述了适用于母乳检测的筛查和确认程序。最后,讨论了母亲向婴儿传播可卡因导致中毒的可能性。给出了婴儿血液中可卡因浓度的估计值,这可能会提高人们在必要情况下监测婴儿母乳和血液中可卡因浓度的意识。

相似文献

1
The routine analysis of breast milk for drugs of abuse in a clinical toxicology laboratory.在临床毒理学实验室对母乳进行滥用药物的常规分析。
J Forensic Sci. 1994 Jan;39(1):207-14.
2
A comparison of meconium, maternal urine and neonatal urine for detection of maternal drug use during pregnancy.用于检测孕期母亲药物使用情况的胎粪、母体尿液和新生儿尿液的比较。
J Forensic Sci. 1994 Jan;39(1):150-8.
3
Maternal and neonatal hair and breast milk in the assessment of perinatal exposure to drugs of abuse.在评估围产期药物滥用暴露情况时的母体和新生儿毛发及母乳。
Bioanalysis. 2015;7(10):1273-97. doi: 10.4155/bio.15.60.
4
Modification of screening immunoassays to detect sub-threshold concentrations of cocaine, cannabinoids, and opiates in urine: use for detecting maternal and neonatal drug exposures.改良筛查免疫分析法以检测尿液中可卡因、大麻素和阿片类药物的亚阈值浓度:用于检测孕产妇和新生儿的药物暴露情况。
Ann Clin Lab Sci. 2000 Jan;30(1):85-91.
5
Detection of fetal cocaine exposure by analysis of amniotic fluid.通过分析羊水检测胎儿可卡因暴露情况。
Obstet Gynecol. 1993 May;81(5 ( Pt 1)):787-90.
6
Gastric fluid analysis for determining gestational cocaine exposure.用于确定孕期可卡因暴露情况的胃液分析。
Pediatrics. 1996 Aug;98(2 Pt 1):291-3.
7
Evaluation of the IDS One-Step ELISA kits for the detection of illicit drugs in hair.用于检测毛发中非法药物的IDS一步式酶联免疫吸附测定试剂盒的评估。
Forensic Sci Int. 2007 Aug 6;170(2-3):189-92. doi: 10.1016/j.forsciint.2007.02.032. Epub 2007 Jul 12.
8
Unsuspected exposure to cocaine in preschool children from a Mediterranean city detected by hair analysis.通过毛发分析检测到地中海城市学龄前儿童中存在未被察觉的可卡因暴露情况。
Ther Drug Monit. 2009 Jun;31(3):391-5. doi: 10.1097/FTD.0b013e31819c3f2b.
9
Detection of cocaine and its metabolites in breast milk.
J Forensic Sci. 2001 Sep;46(5):1221-3.
10
In utero drugs of abuse exposure testing for newborn twins.宫内滥用药物暴露检测在新生儿双胞胎中的应用。
J Clin Pathol. 2010 Mar;63(3):259-61. doi: 10.1136/jcp.2009.067595.

引用本文的文献

1
Maternal cocaine use during breastfeeding.哺乳期母亲可卡因使用。
Can Fam Physician. 2012 Nov;58(11):1218-9.