Tokuhiro N, Suzuki Y, Fukazawa T, Kinoshita S, Nishiguchi H, Yoshida S, Mikami K, Koseki H, Nakamura M, Kasanuki J
Department of Gastroenterology, Matsudo Municipal Hospital.
Nihon Ronen Igakkai Zasshi. 1993 Dec;30(12):1051-7. doi: 10.3143/geriatrics.30.1051.
We studied the characteristic features of gastric ulcers in 50 elderly cases (over 60 years old) concerning 2 points. Initially, we compared the clinical features of the elderly patients with those of the non-elderly (under 60 years old) patients. Secondly, we compared the endoscopic appearance of the atrophic border of elderly patients with that of elderly persons without gastric ulcer, using the Takemoto and Kimura's classification of endoscopic atrophic borders. The results were that elderly patients with gastric ulcer had few symptoms. The symptoms associated with bleeding, however, were recognized. Many of them had some complications. There was no difference in the healing rate at 8 weeks from the beginning of the treatment by histamine H2-receptor blocker (H2 blocker) between the elderly and non-elderly with gastric ulcer. Concerning the endoscopic atrophic border of the elderly persons without ulcers, the number of the open type cases was significantly greater than that of the closed type. On the contrary, in elderly persons with gastric ulcer, the number of the closed type was significantly greater than that of the open type, especially the number of C-2 type was the greatest. The healing rate of the elderly with closed type border was higher than that of elderly cases with open type border in 4 and 8 weeks from the beginning of the treatment.
我们研究了50例60岁以上老年胃溃疡患者的特征,涉及两个方面。首先,我们将老年患者的临床特征与非老年(60岁以下)患者进行了比较。其次,我们使用竹本和木村的内镜下萎缩边界分类法,比较了老年胃溃疡患者与无胃溃疡老年人的内镜下萎缩边界表现。结果显示,老年胃溃疡患者症状较少。然而,与出血相关的症状是存在的。他们中的许多人有一些并发症。老年和非老年胃溃疡患者在使用组胺H2受体阻滞剂(H2阻滞剂)治疗开始后8周的愈合率没有差异。关于无溃疡老年人的内镜下萎缩边界,开放型病例的数量明显多于封闭型。相反,在老年胃溃疡患者中,封闭型的数量明显多于开放型,尤其是C-2型的数量最多。从治疗开始4周和8周时,封闭型边界老年患者的愈合率高于开放型边界老年患者。