Karwautz A, Wöber-Bingöl C, Wöber C
Universitätsklinik für Neuropsychiatrie des Kindes- und Jugendalters, Wien.
Nervenarzt. 1993 Dec;64(12):753-65.
This review of the literature covers classification, epidemiology and clinical aspects of idiopathic headache in childhood and adolescence. In addition, pathogenetic models taking into account the complex involvement of organic, psychological and psychosocial factors are critically reviewed. A general pathogenetic model of migraine may be characterized by a given predisposition, various co-factors which enhance the tendency, and finally, trigger mechanisms which induce an attack. No generally accepted model exists for tension-type headache. In assessing the importance of various factors thought to be related to idiopathic headache, it is necessary to differentiate between causal relation, unspecific association, and coincidence. The aim of this review is to present potential factors influencing headache in childhood and adolescence and to discuss these factors critically with regard to their etiopathogenetic importance. Organic factors seem to be most important in migraine, whereas psychological and (psycho)social factors may influence any type of headache. Briefly, migraine in childhood and adolescence seems to be definitively associated with vegetative dysfunction, abdominal symptoms and hormonal factors and possibly with allergic reactions, whereas a relation to epilepsy can be excluded. There is absolutely no evidence for a typical personality of migraine patients. Various psychic reactions, however, are important in all types of headache. Depression and anxiety in young headache patients seem to be related generally to pain, but not specifically to headache. However, school problems, learning disabilities and stress coping behaviour seem to be related directly to recurrent headache. Additionally, there is evidence that the prevalence of headache is associated with low economic status.
本文献综述涵盖儿童和青少年特发性头痛的分类、流行病学及临床方面。此外,还对考虑到有机、心理和社会心理因素复杂参与的发病机制模型进行了批判性综述。偏头痛的一般发病机制模型可能具有特定的易感性、各种增强这种倾向的协同因素,以及最终诱发发作的触发机制。紧张型头痛不存在普遍接受的模型。在评估各种被认为与特发性头痛相关的因素的重要性时,有必要区分因果关系、非特异性关联和巧合。本综述的目的是介绍影响儿童和青少年头痛的潜在因素,并就其病因学重要性对这些因素进行批判性讨论。有机因素在偏头痛中似乎最为重要,而心理和(心理)社会因素可能影响任何类型的头痛。简而言之,儿童和青少年偏头痛似乎肯定与自主神经功能障碍、腹部症状和激素因素有关,可能还与过敏反应有关,而与癫痫的关系可以排除。绝对没有证据表明偏头痛患者有典型的人格。然而,各种心理反应在所有类型的头痛中都很重要。年轻头痛患者的抑郁和焦虑似乎一般与疼痛有关,但并非专门与头痛有关。然而,学校问题、学习障碍和压力应对行为似乎与复发性头痛直接相关。此外,有证据表明头痛的患病率与低经济地位有关。