Fodor L, Varga J, Gallowitsch F, Horváth-Papp I, Miklós G, Lajcsák A, Harmath A
Department of Microbiology and Infectious Diseases, University of Veterinary Science, Budapest.
Acta Vet Hung. 1993;41(1-2):41-9.
The therapeutic effect of a single injection of tilmicosin (10 mg/kg body mass) against natural cases of pneumonia of calves, compared to other conventionally used antibiotics, was examined under field conditions. The trials were conducted in three cattle herds and included the treatment of 135 calves with 82 controls. The animals' age ranged from 1 week to 4 months. Prior to the treatment and in case of death bacteriological examinations from nasal swabs and from the lungs were carried out. Clinical signs were recorded in all groups and in one group body mass gains were also recorded. After tilmicosin treatment, the body temperature returned to the normal level within 24 h and the animals recovered within 1 to 2 days. Ten calves (7.41%) showed relapse during the 3rd and 4th week after treatment in contrast to 9 (10.98%) in the control group. Three calves (2.22%) died in the groups treated with tilmicosin and 6 calves (7.32%) among the controls. In one of the treated groups the body mass gain was 6.2% higher compared to the controls at the age of 3 months. These results suggest that treatment with a single dose of tilmicosin is effective in most cases of calf pneumonia caused by bacteria.
在田间条件下，将单剂量注射替米考星（10毫克/千克体重）与其他常规使用的抗生素相比，对犊牛自然发生的肺炎病例的治疗效果进行了研究。试验在三个牛群中进行，包括对135头犊牛进行治疗，并设置了82头对照。动物年龄从1周龄到4月龄不等。治疗前以及出现死亡情况时，均对鼻拭子和肺部进行细菌学检查。记录了所有组的临床症状，并且在一组中还记录了体重增加情况。替米考星治疗后，体温在24小时内恢复正常水平，动物在1至2天内康复。治疗后第3周和第4周，10头犊牛（7.41%）出现复发，而对照组为9头（10.98%）。替米考星治疗组中有3头犊牛（2.22%）死亡，对照组中有6头犊牛（7.32%）死亡。在其中一个治疗组中，3月龄时的体重增加比对照组高6.2%。这些结果表明，单剂量替米考星治疗对大多数由细菌引起的犊牛肺炎病例有效。
