Perlow J H, Morgan M A
Department of Obstetrics and Gynecology, Long Beach Memorial Medical Center Women's Hospital, California.
Am J Obstet Gynecol. 1994 Feb;170(2):560-5. doi: 10.1016/s0002-9378(94)70227-6.
Our purpose was to determine the impact of massive maternal obesity (weight > 300 pounds) on perioperative morbidity among patients undergoing cesarean section.
A case-control study was conducted on 43 massively obese pregnant women, identified by perinatal database search, who were delivered by cesarean section between Jan. 1, 1987, and Dec. 31, 1991, at Long Beach Memorial Women's Hospital. Forty-three randomly selected patients who underwent cesarean delivery served as the control group. Medical records were abstracted for perioperative variables and compared between groups. Student t test, chi 2, and Fisher's exact statistical analysis were used where appropriate.
No significant differences were observed between groups for maternal age, parity, use of prophylactic antibiotics, length of recovery room stay, or wound dehiscence. The massively obese group was observed to be at significantly increased risk for emergency cesarean section (32.6% vs 9.3%, p = 0.02), prolonged delivery interval (25.6% vs 4.6%, p = 0.01), and total operative time (48.8% vs 9.3%, p < 0.0001), blood loss > 1000 ml (34.9% vs 9.3%, p = 0.009), multiple epidural placement failures (14.0% vs 0%, p = 0.02), postoperative endometritis (32.6% vs 4.9%, p = 0.002), and prolonged hospitalization (34.9% vs 2.3%, p = 0.0003).
Massively obese pregnant women undergoing cesarean section are at significantly increased risk for perioperative morbidity.
我们的目的是确定孕妇极度肥胖(体重>300磅)对剖宫产患者围手术期发病率的影响。
对43例极度肥胖的孕妇进行了一项病例对照研究,这些孕妇通过围产期数据库搜索确定,于1987年1月1日至1991年12月31日在长滩纪念妇女医院接受剖宫产。43例随机选择的接受剖宫产的患者作为对照组。提取病历中的围手术期变量并在组间进行比较。在适当情况下使用学生t检验、卡方检验和费舍尔精确统计分析。
两组在产妇年龄、产次、预防性抗生素的使用、恢复室停留时间或伤口裂开方面未观察到显著差异。观察到极度肥胖组急诊剖宫产的风险显著增加(32.6%对9.3%,p = 0.02)、分娩间隔延长(25.6%对4.6%,p = 0.01)、总手术时间(48.8%对9.3%,p < 0.0001)、失血>1000 ml(34.9%对9.3%,p = 0.009)、多次硬膜外穿刺失败(14.0%对0%,p = 0.02)、术后子宫内膜炎(32.6%对4.9%,p = 0.002)和住院时间延长(34.9%对2.3%,p = 0.0003)。
接受剖宫产的极度肥胖孕妇围手术期发病风险显著增加。