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母亲体质量指数与分娩时使用椎管内镇痛:基于人群的回顾性队列研究。

Maternal Body Mass Index and Use of Labor Neuraxial Analgesia: A Population-based Retrospective Cohort Study.

机构信息

From the Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, California (A.J.B., N.G.) the University of Iowa Carver College of Medicine, Iowa City, Iowa (C.A.W.).

出版信息

Anesthesiology. 2018 Sep;129(3):448-458. doi: 10.1097/ALN.0000000000002322.

Abstract

WHAT WE ALREADY KNOW ABOUT THIS TOPIC

WHAT THIS ARTICLE TELLS US THAT IS NEW: BACKGROUND:: Neuraxial labor analgesia may benefit obese women by optimizing cardiorespiratory function and mitigating complications related to emergency general anesthesia. We hypothesized that obese women have a higher rate of neuraxial analgesia compared with nonobese parturients.

METHODS

Using U.S. natality data, our cohort comprised 17,220,680 deliveries, which accounts for 61.5% of 28 million births in the United States between 2009 and 2015. We examined the relationships between body mass index class and neuraxial labor analgesia, adjusting for sociodemographic, antenatal, pregnancy, and peripartum factors.

RESULTS

The study cohort comprised 17,220,680 women; 0.1% were underweight, 12.7% were normal body mass index, 37% were overweight, and 28.3%, 13.5%, and 8.4% were obesity class I, II, and III, respectively. Rates of neuraxial analgesia by body mass index class were as follows: underweight, 59.7% (9,030/15,128); normal body mass index, 68.1% (1,487,117/2,182,797); overweight, 70.3% (4,476,685/6,368,656); obesity class I, 71.8% (3,503,321/4,881,938); obesity class II, 73.4% (1,710,099/2,330,028); and obesity class III, 75.6% (1,089,668/1,442,133). Compared to women with normal body mass index, the likelihood of receiving neuraxial analgesia was slightly increased for overweight women (adjusted relative risk, 1.02; 95% CI, 1.02 to 1.02), obese class I (adjusted relative risk, 1.04; 95% CI, 1.04 to 1.04), obese class II (adjusted relative risk, 1.05; 95% CI, 1.05 to 1.05), and obese class III (adjusted relative risk, 1.06; 95% CI, 1.06 to 1.06).

CONCLUSIONS

Our findings suggest that the likelihood of receiving neuraxial analgesia is only marginally increased for morbidly obese women compared to women with normal body mass index.

摘要

我们已知的相关知识

这篇文章告诉我们新的内容:背景:椎管内分娩镇痛可能通过优化心肺功能和减轻与紧急全身麻醉相关的并发症而使肥胖女性受益。我们假设肥胖女性与非肥胖产妇相比,接受椎管内镇痛的比例更高。

方法

利用美国出生数据,我们的队列包括 17220680 例分娩,占 2009 年至 2015 年美国 2800 万分娩中的 61.5%。我们检查了体重指数类别与椎管内分娩镇痛之间的关系,并调整了社会人口学、产前、妊娠和围产期因素。

结果

研究队列包括 17220680 名女性;0.1%为体重不足,12.7%为正常体重指数,37%为超重,28.3%、13.5%和 8.4%分别为肥胖 I 级、II 级和 III 级。按体重指数分类的椎管内镇痛率如下:体重不足,59.7%(9030/15128);正常体重指数,68.1%(1487117/2182797);超重,70.3%(4476685/6368656);肥胖 I 级,71.8%(3503321/4881938);肥胖 II 级,73.4%(1710099/2330028);肥胖 III 级,75.6%(1089668/1442133)。与正常体重指数的女性相比,超重女性(校正相对风险,1.02;95%CI,1.02 至 1.02)、肥胖 I 级(校正相对风险,1.04;95%CI,1.04 至 1.04)、肥胖 II 级(校正相对风险,1.05;95%CI,1.05 至 1.05)和肥胖 III 级(校正相对风险,1.06;95%CI,1.06 至 1.06)接受椎管内镇痛的可能性略有增加。

结论

我们的发现表明,与正常体重指数的女性相比,病态肥胖女性接受椎管内镇痛的可能性仅略有增加。

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