Jauker F
J Cell Biol. 1975 Dec;67(3):901-4. doi: 10.1083/jcb.67.3.901.
Protein and RNA contents of individual cells were measured cytophotometrically and related to the duration of individual generation times. Constant amounts of RNA per cell at division, and generation time-dependent protein contents, resulted in generation time-specific RNA/protein ratios. Experimental reduction of these ratios by inhibition of RNA synthesis stimulated premature macronuclear S phases.
通过细胞光度测定法测量单个细胞的蛋白质和RNA含量,并将其与各个世代时间的持续时间相关联。细胞分裂时每个细胞的RNA量恒定,且蛋白质含量依赖于世代时间,从而产生了特定世代时间的RNA/蛋白质比率。通过抑制RNA合成来实验性降低这些比率,刺激了大核S期的提前出现。