Gannushkina I V, Antelava A L, Baranchikova M V
Biull Eksp Biol Med. 1993 Oct;116(10):367-70.
The experiments on adult rabbits have demonstrated that high-cholesterol diet given to the animals for 3 months causes a severe hypercholesterolemia and disseminated aortic lesion due to the formation of numerous fatty streaks and plaques of atherosclerotic genesis. The simultaneous intravenous injection of a special linear high molecular-weight polymer solution, which reduces hydrodynamic resistance once a week leads to a significantly less atherogenesis in the same hypercholesterolemia. The highest effect was observed in the descending portions of the aorta and just after its bifurcation, i.e. in the areas of the least unsteady blood flow.
对成年兔子的实验表明，给动物喂食3个月的高胆固醇饮食会导致严重的高胆固醇血症和弥漫性主动脉病变，这是由于形成了大量源于动脉粥样硬化的脂肪条纹和斑块。每周同时静脉注射一种特殊的线性高分子聚合物溶液，该溶液可降低流体动力阻力，在相同的高胆固醇血症情况下，可显著减少动脉粥样硬化的发生。在主动脉的降部及其分叉后，即在血流最不稳定的区域观察到了最高的效果。
