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基因组进化模式。

Patterns in genome evolution.

作者信息

Ohno S

机构信息

Department of Theoretical Biology, Beckman Research Institute of the City of Hope, Duarte, California 91010-0269.

出版信息

Curr Opin Genet Dev. 1993 Dec;3(6):911-4. doi: 10.1016/0959-437x(93)90013-f.

Abstract

Among the recent advances that have furthered our understanding of genome evolution, some of the most important information has come from studies on the conservation of the mammalian X chromosome and the conservation of several linkage groups in divergent mammalian species. In addition, I believe that studies on gene duplication by tetraploidy in teleost fish provide evidence that the mammalian ancester underwent a round or two of tetraploid evolution, presumably at the stage of fish. It is possible that we might soon be able to deduce the genomic structure of the Devonian fish ancestor.

摘要

在推动我们对基因组进化理解的近期进展中,一些最重要的信息来自对哺乳动物X染色体保守性以及不同哺乳动物物种中几个连锁群保守性的研究。此外,我认为对硬骨鱼四倍体基因复制的研究提供了证据,表明哺乳动物祖先大概在鱼类阶段经历了一轮或两轮四倍体进化。我们有可能很快就能推断出泥盆纪鱼类祖先的基因组结构。

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